Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3722949 | 0.83 | MMP9 (0.50) | MMP9SIGMAR1KDM4EALDH1A1KMT2A | |
| SCHEMBL27515197 | 0.82 | SIGMAR1 (0.62) | MMP9SIGMAR1KDM4EGAAALDH1A1 | |
| SCHEMBL10822129 | 0.81 | SIGMAR1 (0.47) | MMP9SIGMAR1KDM4EGAAALDH1A1 | |
| SCHEMBL9547586 | 0.79 | L3MBTL1 (0.48) | MMP9SIGMAR1KDM4EALDH1A1TSHR | |
| SCHEMBL28003967 | 0.78 | ALDH1A1 (0.48) | MMP9SIGMAR1KDM4EGAAALDH1A1 | |
| SCHEMBL3216842 | 0.77 | MMP9 (0.47) | MMP9SIGMAR1KDM4EGAAALDH1A1 | |
| SCHEMBL6685262 | 0.75 | SIGMAR1 (0.48) | MMP9SIGMAR1KDM4EGAAALDH1A1 | |
| SCHEMBL2898503 | 0.75 | SIGMAR1 (0.44) | MMP9SIGMAR1KDM4EGAAALDH1A1 | |
| SCHEMBL9547530 | 0.75 | SIGMAR1 (0.51) | MMP9SIGMAR1KDM4EGAAALDH1A1 | |
| SCHEMBL27888752 | 0.75 | MMP9 (0.39) | MMP9SIGMAR1KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |