SCHEMBL28985365

SCHEMBL28985365

Cc1cc(O)nn1-c1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.48
MAPT P10636 5/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ALDH1A1 P00352 7/20 0.44
KDM4E B2RXH2 4/20 0.44
HPGD P15428 4/20 0.44
HSD17B10 Q99714 4/20 0.44
ALOX15 P16050 2/20 0.44
CASP1 P29466 2/20 0.44
NPC1 O15118 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
USP2 O75604 1/20 0.44
RAB9A P51151 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
APAF1 O14727 1/20 0.40
TP53 P04637 1/20 0.40
CASP7 P55210 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401870 0.80 ALDH1A1 (0.46) MAPTKMT2AALDH1A1KDM4EHSD17B10
SCHEMBL28216149 0.75 KMT2A (0.52) SIGMAR1MAPTMEN1KMT2AALDH1A1
SCHEMBL27916120 0.75 NPC1 (0.50) SIGMAR1MAPTMEN1KMT2ANPSR1
SCHEMBL526575 0.72 RAB9A (0.54) SIGMAR1ALDH1A1KDM4ENPC1SMN1; SMN2
SCHEMBL31189136 0.72 RAB9A (0.54) SIGMAR1ALDH1A1KDM4ENPC1SMN1; SMN2
SCHEMBL577642 0.72 MAPK1 (0.56) NPC1SMN1; SMN2RAB9AMAPK1NPY5R
SCHEMBL25295319 0.72 MAPT (0.44) SIGMAR1MAPTMEN1KMT2ANPSR1
SCHEMBL29404918 0.72 MAPT (0.44) SIGMAR1MAPTMEN1KMT2ANPSR1
SCHEMBL859246 0.71 NPC1 (0.50) SIGMAR1MAPTMEN1KMT2ANPSR1
SCHEMBL11478440 0.71 SMN1; SMN2 (0.56) MAPTMEN1KMT2ANPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819348-B Process for preparing N-aryl pyrazole compound 曲靖师范学院 2025-03-21 CN disclosed
CN-115819348-A Process for preparing N-arylpyrazole compound 曲靖师范学院 2023-03-21 CN disclosed