Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451017 | 0.89 | KMT2A (0.49) | KMT2AGAAMAPTALDH1A1HPGD | |
| SCHEMBL21882083 | 0.83 | PDE10A (0.49) | KMT2AGAAMAPTALDH1A1CYP1A2 | |
| SCHEMBL3299372 | 0.80 | KMT2A (0.68) | KMT2AGAAMAPTALDH1A1TP53 | |
| SCHEMBL1740575 | 0.80 | KDM4E (0.57) | KMT2AGAAMAPTALDH1A1TP53 | |
| SCHEMBL3180834 | 0.79 | SLC22A12 (0.47) | KMT2AGAAMAPTALDH1A1HPGD | |
| SCHEMBL29766586 | 0.78 | THRB (0.47) | KMT2AGAAMAPTALDH1A1CYP1A2 | |
| SCHEMBL25897479 | 0.78 | THRB (0.47) | KMT2AGAAMAPTALDH1A1CYP1A2 | |
| SCHEMBL2258851 | 0.76 | TP53 (0.50) | KMT2AGAAMAPTALDH1A1CYP1A2 | |
| SCHEMBL6312871 | 0.76 | ALDH1A1 (0.56) | KMT2AMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4509089 | 0.76 | CYP1A2 (0.49) | KMT2AGAAMAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003267-B | Sigma receptor inhibitors | 埃斯特韦实验室有限公司 | 2018-05-25 | — | — | CN | disclosed |