SCHEMBL28985698

SCHEMBL28985698

Cc1cn(CC(=O)N(S)S)c(=O)[nH]c1=O

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.49
HPGD P15428 1/20 0.48
TYMP P19971 2/20 0.46
TK1 P04183 2/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28985685 0.85 LMNA (0.50) MAPK1HPGDTYMPTK1
SCHEMBL17013819 0.82 MAPK1 (0.56) MAPK1HPGDTYMPTK1
SCHEMBL11983370 0.80 MAPK1 (0.54) MAPK1HPGDTYMPTK1
SCHEMBL456749 0.80 HPGD (0.57) MAPK1HPGDTYMPTK1
SCHEMBL3516690 0.79 KMT2A (0.68) MAPK1HPGDTYMPTK1KMT2A
SCHEMBL5353008 0.79 HPGD (0.55) MAPK1HPGDTYMPTK1
SCHEMBL452185 0.79 MAPK1 (0.53) MAPK1HPGDTYMPTK1
SCHEMBL7643586 0.78 MAPK1 (0.51) MAPK1HPGDTYMPTK1KMT2A
SCHEMBL17013820 0.77 MAPK1 (0.54) MAPK1HPGDTYMPTK1
SCHEMBL3926875 0.76 TK1 (0.40) MAPK1HPGDTYMPTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960480-B Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-09-12 CN claimed
CN-115960480-A Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-04-14 CN claimed
CN-115960480-B Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-09-12 CN disclosed