SCHEMBL28986942

SCHEMBL28986942

COC(=O)c1cc(O)ccc1N(C)c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
PDK2 Q15119 2/20 0.46
PDK4 Q16654 2/20 0.46
SLC6A3 Q01959 1/20 0.40
NR4A2 P43354 1/20 0.39
ALDH1A1 P00352 4/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
HPGD P15428 2/20 0.38
TUBB4A P04350 2/20 0.38
TUBB P07437 2/20 0.38
TUBA3C P0DPH7 2/20 0.38
TUBA1B P68363 2/20 0.38
TUBA4A P68366 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28984841 0.84 MCL1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL5311696 0.79 CA1 (0.62) CA12CA1CA2CA7CA9
SCHEMBL28984844 0.77 MAOB (0.44) CA1CA2PDK2PDK4ALDH1A1
SCHEMBL10835203 0.77 KMT2A (0.55) CA12CA1CA2CA7CA9
SCHEMBL21359274 0.76 SLC6A3 (0.45) SLC6A3NR4A2ALDH1A1GAAMAPT
SCHEMBL28984834 0.76 ALOX15 (0.41) ALDH1A1GAAMAPTKDM4EHPGD
SCHEMBL4302570 0.74 NR4A2 (0.49) CA12CA1CA2CA7CA9
SCHEMBL28984839 0.73 ALOX15 (0.39) ALDH1A1MAPTKDM4EHPGDHSD17B10
SCHEMBL28984819 0.73 HSD17B10 (0.39) CA12CA1CA2CA7CA9
SCHEMBL177377 0.72 CA12 (0.67) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805093-B Preparation method of diarylamines 暨南大学 2023-04-25 CN disclosed
CN-114805093-A Preparation method of diarylamine compound 暨南大学 2022-07-29 CN disclosed