Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.62 |
| ▸ | CA2 | P00918 | 7/20 | 0.62 |
| ▸ | CA12 | O43570 | 6/20 | 0.62 |
| ▸ | CA7 | P43166 | 6/20 | 0.62 |
| ▸ | CA9 | Q16790 | 6/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.62 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.58 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122553 | 0.82 | KDM4E (0.54) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6161036 | 0.81 | GAA (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4302570 | 0.81 | NR4A2 (0.49) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4362314 | 0.81 | ABL1 (0.56) | LMNAGAAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31052715 | 0.81 | KMT2A (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL472317 | 0.79 | ALDH1A1 (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL158999 | 0.79 | CA12 (0.74) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28986942 | 0.79 | CA12 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL22445648 | 0.79 | EGFR (0.42) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4211530 | 0.78 | ALDH1A1 (0.50) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |