Biguanide

Biguanide

SCHEMBL28987306

N=C(N)NC(=N)N.OCCO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biguanide SCHEMBL18255803 0.84 MAPK1 (0.31)
Biguanide SCHEMBL8039 0.84
Biguanide SCHEMBL1428352 0.81
Biguanide SCHEMBL5489883 0.81
Biguanide SCHEMBL31013828 0.81
Biguanide SCHEMBL10881314 0.81
Biguanide SCHEMBL675101 0.81
Biguanide SCHEMBL4221594 0.81
Biguanide SCHEMBL4217126 0.81
Biguanide SCHEMBL28838005 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116004509-A Tissue engineering skin with multilayer epidermal cells and preparation method and application thereof 中国科学院理化技术研究所 2023-04-25 CN claimed
CN-116004509-A Tissue engineering skin with multilayer epidermal cells and preparation method and application thereof 中国科学院理化技术研究所 2023-04-25 CN disclosed