SCHEMBL809404

SCHEMBL809404

C=Cc1ccc(CCl)cc1C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
TTR P02766 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29467223 1.00 KDM4E (0.36) KDM4ECYP3A4CYP2C19HIF1AESR1
SCHEMBL810147 0.84 KDM4E (0.33) KDM4ECYP3A4CYP2C19HIF1ATTR
SCHEMBL1264062 0.82 TRPA1 (0.39) KDM4EESR1ESR2ALDH1A1
SCHEMBL17892818 0.80 ALDH1A1 (0.47) KDM4ECYP3A4ALDH1A1
SCHEMBL28987609 0.80 ALDH1A1 (0.43) KDM4ECYP3A4CYP2C19HIF1AALDH1A1
SCHEMBL31484571 0.80 HSD17B10 (0.40) ESR1ESR2
SCHEMBL9156124 0.80 HRH3 (0.34) ESR1ESR2
SCHEMBL31670525 0.78 SKP2 (0.42) CYP3A4CYP2C19
SCHEMBL1264548 0.78 ALDH1A1 (0.31) ALDH1A1
SCHEMBL809726 0.78 ALDH1A1 (0.45) KDM4ECYP3A4CYP2C19HIF1ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017116272-A1 METHOD FOR PREPARING TERTIARY AMINES COMPRISING ETHYNYLBENZYL SUBSTITUENTS PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2017-07-06 WO claimed
EP-3983418-B1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-11-05 EP disclosed
CN-113939522-B Organosilane, ionic organosilane, film composition and film 3M创新有限公司 2024-12-17 CN disclosed
US-12122797-B2 Organosilane, ionic organosilane, membrane composition, and membrane 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-10-22 US disclosed
US-20220251120-A1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE US DEPARTMENT OF ENERGY 2022-08-11 US disclosed
EP-3983418-A1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE 3M Innovative Properties Company (US) 2022-04-20 EP disclosed
CN-113939522-A Organosilane, ionic organosilane, film composition and film 3M创新有限公司 2022-01-14 CN disclosed
WO-2020254930-A1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-12-24 WO disclosed
US-9896551-B2 Phosphaphenanthrene-based compound and related preparation method and application Elite Electronic Material(Zhongshan) Co., Ltd. (CN) 2018-02-20 US disclosed
WO-2017116272-A1 METHOD FOR PREPARING TERTIARY AMINES COMPRISING ETHYNYLBENZYL SUBSTITUENTS PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2017-07-06 WO disclosed
US-20170022228-A1 PHOSPHAPHENANTHRENE-BASED COMPOUND AND RELATED PREPARATION METHOD AND APPLICATION Elite Electronic Material(Zhongshan) Co., Ltd. (CN) 2017-01-26 US disclosed
WO-2012015977-A3 HIGHLY PORTABLE AND STABLE WORK STATION HERSCHLER MATTHEW B (US) 2012-05-10 WO disclosed
EP-2192645-B1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORP (JP) 2011-11-30 EP disclosed
US-20110250525-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORPORATION (JP) 2011-10-13 US disclosed
EP-2192645-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME Tokuyama Corporation (JP) 2010-06-02 EP disclosed
US-5138001-A Optical disc substrates; low birefringence, heat and moisture absorption resistance, high transparency TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1992-08-11 US disclosed
EP-0415729-A2 Vinylphenyl compound, process for the production thereof, polymerizable composition containing same, and crosslinked polymer formed therefrom TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed
US-4680342-A Flame resistant alkenyl aromatic compounds and polymers containing chemically bonded phosphorus and blends with polyphenylene ether GENERAL ELECTRIC COMPANY (US) 1987-07-14 US disclosed
EP-0147724-A2 Flame resistant alkenyl aromatic compounds and polymers containing chemically bonded phosphorus and blends with polyphenylene ether GENERAL ELECTRIC COMPANY (US) 1985-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251120-A1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE PHOSPHO1, ARRB1, OR51E2 KDM4E 2873/4885CYP3A4 2878/4885CYP2C19 2682/4885
US-20170022228-A1 PHOSPHAPHENANTHRENE-BASED COMPOUND AND RELATED PREPARATION METHOD AND APPLICATION BMI1, RPL23A, P2RY14 KDM4E 806/4885CYP3A4 1793/4885CYP2C19 403/4885
US-12122797-B2 Organosilane, ionic organosilane, membrane composition, and membrane PHOSPHO1, ARRB1, OR51E2 KDM4E 2873/4885CYP3A4 2878/4885CYP2C19 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.