Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704056 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL21151467 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL28987609 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL30216932 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL13177068 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL31056330 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL10239020 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL2036405 | 0.78 | LMNA (0.39) | ALDH1A1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL10777048 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL20017809 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRNPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129077-A1 | SUBSTITUTED PURINES AS TLR7 AGONISTS | Primmune Therapeutics, Inc. | 2025-04-24 | — | — | US | disclosed |
| EP-4512816-A2 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| CN-112533607-B | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-3801538-B1 | TLR7 AGONISTS | PRIMMUNE THERAPEUTICS INC (US) | 2024-10-02 | — | — | EP | disclosed |
| US-12037335-B2 | Substituted purines as TLR7 agonists | Primmune Therapeutics, Inc. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20220098198-A1 | SUBSTITUTED PURINES AS TLR7 AGONISTS | Primmune Therapeutics, Inc. | 2022-03-31 | — | — | US | disclosed |
| US-11059824-B2 | Substituted purines as TLR7 agonists | Primmune Therapeutics, Inc. (US) | 2021-07-13 | — | — | US | disclosed |
| EP-3801538-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| CN-112533607-A | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2021-03-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059824-B2 | Substituted purines as TLR7 agonists | TLR7, TLR9, TLR1 | ALDH1A1 934/4885TSHR 1300/4885NPC1 685/4885 |
| US-12037335-B2 | Substituted purines as TLR7 agonists | TLR7, TLR9, TLR1 | ALDH1A1 934/4885TSHR 1300/4885NPC1 685/4885 |
| US-20220098198-A1 | SUBSTITUTED PURINES AS TLR7 AGONISTS | TLR7, TLR9, TLR1 | ALDH1A1 934/4885TSHR 1300/4885NPC1 685/4885 |
| US-20250129077-A1 | SUBSTITUTED PURINES AS TLR7 AGONISTS | TLR7, TLR9, TLR1 | ALDH1A1 934/4885TSHR 1300/4885NPC1 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.