Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624148 | 0.76 | NPC1 (0.64) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL2815533 | 0.72 | MAPT (0.44) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| Bromide SCHEMBL2818346 | 0.71 | MAPT (0.43) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL8288559 | 0.70 | TP53 (0.59) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL20970019 | 0.68 | KDM4E (0.48) | KDM4EALDH1A1HPGDAKT1AKT2 | |
| SCHEMBL16332036 | 0.68 | MAPK14 (0.47) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2906472 | 0.68 | GABRA1 (0.42) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL30957114 | 0.68 | GAA (0.54) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL30847319 | 0.68 | AKT1 (0.50) | NPC1RAB9AALDH1A1AKT1AKT2 | |
| SCHEMBL14622550 | 0.67 | AKT2 (0.51) | NPC1RAB9AKDM4ENTRK1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216052-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-11 | — | — | EP | disclosed |