Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.38 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817090 | 0.84 | CYP11B1 (0.53) | GABRA1GABRB2ALDH1A1TP53POLB | |
| SCHEMBL22615061 | 0.81 | SLC2A3 (0.46) | GABRA1GABRB2ALDH1A1TP53MAPT | |
| SCHEMBL30847319 | 0.81 | AKT1 (0.50) | GABRA1GABRB2ALDH1A1NR1H4MAPK14 | |
| SCHEMBL22615058 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TP53MAPTMAPK13MAPK12 | |
| SCHEMBL15824701 | 0.76 | SLC2A1 (0.54) | TP53MAPTMAPK14SLC2A1SLC2A3 | |
| SCHEMBL2905517 | 0.74 | RAB9A (0.45) | ALDH1A1MAPTNR1H4SLC2A1KDM4E | |
| SCHEMBL2904371 | 0.69 | APP (0.66) | ALDH1A1TP53POLBSLC2A1KDM4E | |
| SCHEMBL1394183 | 0.69 | AKT1 (0.40) | ALDH1A1SIRT5MAPK14KDM4EAKT1 | |
| SCHEMBL2815533 | 0.69 | MAPT (0.44) | ALDH1A1TP53MAPTKDM4EHPGD | |
| SCHEMBL2429185 | 0.68 | LMNA (0.40) | ALDH1A1POLBMAPK14KDM4ECYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216052-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-11 | — | — | EP | disclosed |