SCHEMBL30847319

SCHEMBL30847319

Fc1ccc2nc(-c3ccccc3)c(I)n2c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ AKT1 P31749 1/20 0.50
▸ AKT2 P31751 1/20 0.50
▸ CYP11B1 P15538 8/20 0.48
▸ CYP11B2 P19099 8/20 0.48
▸ SLC2A1 P11166 1/20 0.43
▸ NR1H4 Q96RI1 1/20 0.42
▸ GABRA1 P14867 2/20 0.42
▸ GABRB2 P47870 2/20 0.42
▸ NPC1 O15118 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ ALDH1A3 P47895 1/20 0.41
▸ CYP19A1 P11511 2/20 0.40
▸ TRPA1 O75762 2/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ HTR6 P50406 1/20 0.40
▸ MAPK14 Q16539 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22615061 0.84 SLC2A3 (0.46) AKT1AKT2CYP11B1CYP11B2SLC2A1
SCHEMBL15730473 0.81 AKT1 (0.56) AKT1AKT2CYP11B1CYP11B2SLC2A1
SCHEMBL2906472 0.81 GABRA1 (0.42) AKT1AKT2CYP11B1CYP11B2SLC2A1
Hydrochloric Acid SCHEMBL18128834 0.79 AKT1 (0.55) AKT1AKT2CYP11B1CYP11B2SLC2A1
SCHEMBL22615058 0.77 ALDH1A1 (0.62) NPC1RAB9AALDH1A1MAPK14
SCHEMBL4833235 0.76 NPC1 (0.64) AKT1AKT2SLC2A1NPC1RAB9A
SCHEMBL14810130 0.73 CYP11B2 (0.38) CYP11B1CYP11B2GABRA1GABRB2CYP19A1
SCHEMBL16540967 0.73 CYP11B1 (0.43) CYP11B1CYP11B2GABRA1GABRB2ALDH1A1
SCHEMBL1318629 0.71 AKT1 (0.53) AKT1AKT2CYP11B1CYP11B2ALDH1A3
SCHEMBL15824701 0.70 SLC2A1 (0.54) SLC2A1NPC1RAB9AMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027124-A1 SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT AND PREVENTION OF FIBROSIS MOEXA PHARMACEUTICALS LTD (CN) 2026-01-29 — — US disclosed
EP-4558503-A1 SUBSTITUTED IMIDAZO [1, 2-A] PYRIDINE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT AND PREVENTION OF FIBROSIS Moexa Pharmaceuticals Limited (HK) 2025-05-28 — — EP disclosed
WO-2024017144-A1 SUBSTITUTED IMIDAZO [1, 2-A] PYRIDINE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT AND PREVENTION OF FIBROSIS MOEXA PHARMACEUTICALS LIMITED (CN) 2024-01-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027124-A1 SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT AND PREVENTION OF FIBROSIS NOX4, NOX1, CBR1 AKT1 2208/4885AKT2 1993/4885CYP11B1 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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