Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681889 | 1.00 | LMNA (0.38) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31681888 | 0.80 | POLB (0.42) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28988937 | 0.80 | POLB (0.42) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5806384 | 0.75 | NTRK1 (0.55) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2827976 | 0.72 | LMNA (0.46) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28989269 | 0.72 | KDM4E (0.40) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31681893 | 0.72 | KDM4E (0.40) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5806826 | 0.72 | MAPT (0.49) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5807865 | 0.70 | PTGS1 (0.52) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5804750 | 0.70 | ALDH1A1 (0.53) | LMNAKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991698-B | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115991698-A | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2023-04-21 | — | — | CN | disclosed |