Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.51 |
| ▸ | CTSK | P43235 | 10/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24981989 | 1.00 | CTSS (0.51) | CTSSCTSKCTSBAAK1CTSL | |
| SCHEMBL19858727 | 0.85 | CTSS (0.52) | CTSSCTSKCTSBAAK1CTSL | |
| SCHEMBL16064303 | 0.85 | CTSS (0.52) | CTSSCTSKCTSBAAK1CTSL | |
| SCHEMBL28989419 | 0.82 | TACR1 (0.48) | CTSSCTSKCTSBAAK1 | |
| SCHEMBL24981981 | 0.82 | TACR1 (0.48) | CTSSCTSKCTSBAAK1 | |
| SCHEMBL24981983 | 0.82 | ACE (0.49) | CTSSCTSKCTSBAAK1 | |
| SCHEMBL28989259 | 0.82 | ACE (0.49) | CTSSCTSKCTSBAAK1 | |
| SCHEMBL26781565 | 0.81 | AAK1 (0.47) | CTSSCTSKCTSBAAK1 | |
| SCHEMBL28989403 | 0.81 | AAK1 (0.47) | CTSSCTSKCTSBAAK1 | |
| SCHEMBL2617400 | 0.80 | CTSS (0.65) | CTSSCTSKCTSBAAK1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996923-A | Nitrile derivative as dipeptidyl peptidase 1 inhibitor and application thereof | 四川海思科制药有限公司 | 2023-04-21 | — | — | CN | disclosed |