Boric Acid

Boric Acid

SCHEMBL28989883

CC(C)(O)C(C)(C)O.Cc1cccc(Nc2ccccc2)c1C.OB(O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
CYP3A4 P08684 2/20 0.49
LMNA P02545 2/20 0.49
PTGS2 P35354 2/20 0.49
AKR1B10 O60218 1/20 0.49
TRPA1 O75762 1/20 0.49
ABCB11 O95342 1/20 0.49
DHFR P00374 1/20 0.49
MPO P05164 1/20 0.49
CYP1A2 P05177 1/20 0.49
CHRM1 P11229 1/20 0.49
CYP2C9 P11712 1/20 0.49
AKR1B1 P15121 1/20 0.49
PTGS1 P23219 1/20 0.49
AKR1C3 P42330 1/20 0.49
AKR1C2 P52895 1/20 0.49
AKR1C1 Q04828 1/20 0.49
HIF1A Q16665 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30594032 0.85 MEN1 (0.58) MEN1KMT2ATDP1CYP3A4LMNA
SCHEMBL429858 0.85 MEN1 (0.58) MEN1KMT2ATDP1CYP3A4LMNA
SCHEMBL29550941 0.81 TDP1 (0.54) MEN1KMT2ATDP1CYP3A4LMNA
SCHEMBL22772445 0.81 TDP1 (0.54) MEN1KMT2ATDP1CYP3A4LMNA
SCHEMBL28989947 0.81 RAPGEF4 (0.42) MEN1KMT2ATDP1CYP3A4LMNA
Boric Acid SCHEMBL28989881 0.80 HRH3 (0.38) MEN1KMT2ATDP1CYP3A4LMNA
Boric Acid SCHEMBL30411752 0.80 MAPT (0.42) MEN1KMT2ATDP1CYP3A4LMNA
Diphenylamine SCHEMBL28969520 0.79 HSD17B10 (0.55) MEN1KMT2ATDP1CYP3A4LMNA
SCHEMBL1922752 0.77 RAPGEF4 (0.59) MEN1KMT2ATDP1CYP3A4LMNA
SCHEMBL7974336 0.76 RAPGEF4 (0.53) MEN1KMT2ATDP1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023392-A Synthesis and application of benzo [1,2-c:4,5-c' -bis ([ 1,2,5] thiadiazole) dye 南京信息工程大学 2023-04-28 CN disclosed