Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990550 | 0.90 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2D6NFKB1PNMT | |
| SCHEMBL28990758 | 0.90 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2D6NFKB1PNMT | |
| SCHEMBL28990632 | 0.89 | CASP1 (0.38) | P2RX7GLAALDH1A1AVPR2AVPR1A | |
| SCHEMBL28990667 | 0.89 | CASP1 (0.38) | P2RX7GLAALDH1A1AVPR2AVPR1A | |
| SCHEMBL28990700 | 0.85 | HPGD (0.38) | P2RX7GLAALDH1A1MEN1KMT2A | |
| SCHEMBL257268 | 0.81 | PNMT (0.42) | CYP1A2CYP3A4CYP2D6NFKB1PNMT | |
| SCHEMBL28990639 | 0.81 | HPGD (0.37) | P2RX7GLAALDH1A1AVPR2AVPR1A | |
| SCHEMBL28990797 | 0.81 | HPGD (0.37) | P2RX7GLAALDH1A1AVPR2AVPR1A | |
| SCHEMBL28990596 | 0.79 | AVPR2 (0.35) | P2RX7AVPR2AVPR1A | |
| SCHEMBL28990740 | 0.78 | HPGD (0.41) | ALDH1A1LMNAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |