Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041589 | 0.90 | ABCB1 (0.37) | ABCB1POLBTSHRCYP3A4CYP2C9 | |
| SCHEMBL28041542 | 0.87 | POLB (0.38) | POLBPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL28041541 | 0.82 | KDM4E (0.36) | ABCB1POLBNPC1RAB9ATSHR | |
| SCHEMBL28990602 | 0.79 | POLB (0.34) | POLBPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL27992397 | 0.78 | POLB (0.39) | POLBPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL28041744 | 0.77 | CASP1 (0.40) | RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL28041751 | 0.77 | GAA (0.40) | ABCB1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL20554973 | 0.75 | CNR2 (0.38) | POLBPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL28990777 | 0.72 | CNR2 (0.44) | POLBPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL16054823 | 0.72 | KEAP1 (0.37) | TSHRCYP2C9CYP2C19HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |