Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 12/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990749 | 0.87 | CASP1 (0.43) | CASP1CTSAOPRM1OPRL1MEN1 | |
| SCHEMBL28041589 | 0.86 | ABCB1 (0.37) | MEN1KMT2A | |
| SCHEMBL28041751 | 0.85 | GAA (0.40) | CTSAMEN1KMT2AALDH1A1 | |
| SCHEMBL28041525 | 0.85 | CTSA (0.39) | CASP1CTSAOPRM1OPRL1MEN1 | |
| SCHEMBL27992133 | 0.77 | CASP1 (0.46) | CASP1CTSAKCNQ2ALDH1A1 | |
| SCHEMBL28990776 | 0.77 | ABCB1 (0.36) | MEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL15067314 | 0.74 | POLB (0.41) | CASP1CTSAOPRM1OPRL1MEN1 | |
| SCHEMBL11244690 | 0.73 | CXCL8 (0.44) | CASP1CTSAOPRM1OPRL1MEN1 | |
| SCHEMBL23347634 | 0.73 | CASP1 (0.40) | CASP1CTSA | |
| SCHEMBL250307 | 0.73 | CASP1 (0.40) | CASP1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-104136416-B | Phenylalkylamino carbamate derivatives compound and comprise the pharmaceutical composition of this Phenylalkylamino carbamate derivatives compound | 比皮艾思药物研发有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105209027-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | BIO PHARM SOLUTIONS CO LTD | 2015-12-30 | — | — | CN | disclosed |