Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420831 | 0.72 | GABRP (0.46) | TSHRALDH1A1ENPEP | |
| SCHEMBL2068783 | 0.71 | TSHR (0.48) | TSHRALDH1A1LMNASLC22A6ENPEP | |
| SCHEMBL22555513 | 0.71 | CYP1A2 (0.45) | TSHR | |
| SCHEMBL387923 | 0.70 | TSHR (0.46) | TSHRALDH1A1LMNASLC22A6ENPEP | |
| Glutarate SCHEMBL29217352 | 0.69 | SLC22A6 (0.73) | TSHRALDH1A1LMNASLC22A6NFKB1 | |
| Adipic Acid SCHEMBL12980634 | 0.69 | LMNA (0.73) | TSHRALDH1A1LMNASLC22A6NFKB1 | |
| SCHEMBL4358234 | 0.68 | TSHR (0.45) | TSHRALDH1A1LMNASLC22A6ENPEP | |
| SCHEMBL26129724 | 0.68 | TSHR (0.45) | TSHRALDH1A1LMNASLC22A6ENPEP | |
| SCHEMBL125280 | 0.67 | — | — | |
| SCHEMBL11692997 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527932-A | REACTION PRODUCT OF AMINE, UNSATURATED EPOXY COMPOUNDS AND SILICON COMPOUND WITH AT LEAST TWO SILICON-BONDED ALKOXY GROUPS | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1996-06-18 | — | — | US | claimed |