Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28992876 | 0.91 | MMP8 (0.41) | MMP8MAPTHIF1AAPLNRLMNA | |
| SCHEMBL28992903 | 0.87 | MMP8 (0.39) | MMP8MAPTHIF1AAPLNRLMNA | |
| SCHEMBL28992900 | 0.82 | MAPT (0.34) | MMP8MAPTHIF1AALOX15APLNR | |
| SCHEMBL28992870 | 0.80 | APLNR (0.36) | APLNR | |
| SCHEMBL28992874 | 0.75 | MMP8 (0.38) | MMP8MAPTHIF1AALOX15CYP4F2 | |
| SCHEMBL1861113 | 0.72 | PKM (0.54) | MAPTHIF1ALMNA | |
| SCHEMBL30326594 | 0.72 | MMP8 (0.43) | MMP8ALOX15LMNACYP4F2CYP4A11 | |
| SCHEMBL20565608 | 0.71 | MAPT (0.37) | MMP8MAPTHIF1ALMNACYP4F2 | |
| SCHEMBL12632001 | 0.70 | PKM (0.41) | MAPTLMNACYP4F2CYP4A11 | |
| SCHEMBL18084133 | 0.68 | MMP8 (0.40) | MMP8MAPTCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872927-A | AAK1 inhibitors and uses thereof | 武汉人福创新药物研发中心有限公司 | 2023-03-31 | — | — | CN | disclosed |