Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.37 |
| ▸ | CIT | O14578 | 2/20 | 0.37 |
| ▸ | GAK | O14976 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | BMP2K | Q9NSY1 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30326268 | 1.00 | CTSB (0.43) | CTSBAAK1GLO1SYKNSD2 | |
| SCHEMBL30326250 | 0.81 | PIK3CD (0.43) | CYP3A4MEN1KMT2ASLC6A2BRD4 | |
| SCHEMBL28992908 | 0.81 | PIK3CD (0.43) | CYP3A4MEN1KMT2ASLC6A2BRD4 | |
| SCHEMBL8035513 | 0.77 | CKS1B (0.46) | CTSBGLO1SYKNSD2CASP6 | |
| SCHEMBL1506959 | 0.71 | HTR1A (0.53) | SYKNSD2CASP6G6PDMEN1 | |
| SCHEMBL28992906 | 0.70 | AAK1 (0.46) | AAK1DYRK1ACYP3A4PRKG2CIT | |
| SCHEMBL15698806 | 0.68 | DRD1 (0.43) | CTSBSYKNSD2CASP6G6PD | |
| SCHEMBL13036181 | 0.67 | KMT2A (0.50) | SYKNSD2CASP6G6PDMEN1 | |
| SCHEMBL14288341 | 0.66 | GAA (0.45) | SYKNSD2CASP6G6PDMEN1 | |
| SCHEMBL28992891 | 0.66 | DYRK1A (0.60) | AAK1SYKDYRK1ACYP3A4PRKG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872927-A | AAK1 inhibitors and uses thereof | 武汉人福创新药物研发中心有限公司 | 2023-03-31 | — | — | CN | disclosed |