SCHEMBL28993181

SCHEMBL28993181

CC(C)(O)C(C)(C)Oc1ccccc1.OBO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.36
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
PPARG P37231 5/20 0.34
LTA4H P09960 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 1/20 0.33
PPARA Q07869 4/20 0.33
CYP2D6 P10635 2/20 0.32
CYP2C19 P33261 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK1 P28482 1/20 0.32
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
PDK1 Q15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27617060 0.91 CA4 (0.39) CA4ALDH1A1ALOX15PPARGLTA4H
SCHEMBL1022162 0.91 CA4 (0.39) CA4ALDH1A1ALOX15PPARGLTA4H
SCHEMBL28993166 0.89 NPC1 (0.40) ALDH1A1PPARGTSHRPPARACYP2C19
Boric Acid SCHEMBL28167570 0.88 CA1 (0.36) CA4ALDH1A1ALOX15PPARGLTA4H
SCHEMBL7533166 0.88 CA4 (0.36) CA4ALDH1A1ALOX15PPARGLTA4H
Boric Acid SCHEMBL28318217 0.86 CA1 (0.35) CA4ALDH1A1ALOX15PPARGLTA4H
SCHEMBL28993186 0.82 CA1 (0.44) ALDH1A1LTA4HL3MBTL1CYP3A4MAPT
SCHEMBL28993178 0.82 ACHE (0.38) ALDH1A1L3MBTL1TSHRPPARACYP2D6
SCHEMBL28993179 0.80 PPARA (0.50) ALDH1A1ALOX15PPARGATML3MBTL1
SCHEMBL28993188 0.80 GAA (0.36) ALDH1A1PPARGPPARACYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874244-A Preparation method of arylboronic acid ester or alkyl boronate compound 中国科学院兰州化学物理研究所 2022-08-09 CN disclosed