SCHEMBL28993178

SCHEMBL28993178

Cc1ccc(OC(C)(C)C(C)(C)O)cc1.OBO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.38
LMNA P02545 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
TSHR P16473 2/20 0.33
CYP3A4 P08684 2/20 0.33
TEAD4 Q15561 1/20 0.33
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
TDP1 Q9NUW8 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
WDR5 P61964 1/20 0.32
POLB P06746 1/20 0.32
PPARA Q07869 3/20 0.32
PPARD Q03181 1/20 0.32
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Boric Acid SCHEMBL28233693 0.88 ACHE (0.38) ACHELMNACA1CA2CA9
SCHEMBL28993186 0.84 CA1 (0.44) ACHECA1CA2CA9CYP3A4
SCHEMBL28993171 0.82 MEN1 (0.35) LMNACA1CA2CA9TSHR
SCHEMBL28993179 0.82 PPARA (0.50) ACHELMNATSHRCYP3A4MEN1
SCHEMBL28993188 0.82 GAA (0.36) CYP3A4MEN1KMT2AALDH1A1MAPT
SCHEMBL28993181 0.82 CA4 (0.36) LMNATSHRCYP3A4MEN1KMT2A
SCHEMBL28993195 0.79 CA1 (0.41) CA1CA2CA9CYP3A4ALDH1A1
SCHEMBL28993166 0.79 NPC1 (0.40) LMNACA1CA2CA9TSHR
SCHEMBL28993183 0.79 NR1H2 (0.39) ACHECYP3A4MEN1KMT2AMAPT
SCHEMBL28993170 0.78 ACHE (0.46) ACHELMNAKMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874244-A Preparation method of arylboronic acid ester or alkyl boronate compound 中国科学院兰州化学物理研究所 2022-08-09 CN disclosed