Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATIC | P31939 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354703 | 0.84 | ACLY (0.34) | ACLY | |
| SCHEMBL30286458 | 0.84 | ACLY (0.34) | ACLY | |
| SCHEMBL30286541 | 0.76 | ACLY (0.43) | ATICACLY | |
| SCHEMBL20354880 | 0.76 | ACLY (0.43) | ATICACLY | |
| SCHEMBL20354786 | 0.75 | IDO1 (0.44) | MEN1MAPTKMT2AATICMAP2K4 | |
| SCHEMBL30286691 | 0.75 | IDO1 (0.44) | MEN1MAPTKMT2AATICMAP2K4 | |
| SCHEMBL20354888 | 0.72 | ACLY (0.41) | MAPTKMT2AATICACLY | |
| SCHEMBL30286588 | 0.72 | ACLY (0.41) | MAPTKMT2AATICACLY | |
| SCHEMBL20340324 | 0.71 | ACLY (0.43) | ACLY | |
| SCHEMBL20340339 | 0.71 | SLC22A12 (0.39) | ATICACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |