Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 15/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | SGK1 | O00141 | 2/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354703 | 1.00 | ACLY (0.34) | ACLYPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL20340324 | 0.85 | ACLY (0.43) | ACLYSGK1 | |
| SCHEMBL28993276 | 0.84 | MEN1 (0.32) | ACLY | |
| SCHEMBL30286579 | 0.82 | ACLY (0.39) | ACLYSLC40A1 | |
| SCHEMBL21545848 | 0.82 | ACLY (0.39) | ACLYSLC40A1 | |
| SCHEMBL20340304 | 0.81 | PTGES2 (0.41) | ACLY | |
| SCHEMBL20355177 | 0.81 | ACLY (0.42) | ACLYPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30286537 | 0.81 | ACLY (0.42) | ACLYPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL20340313 | 0.79 | ACLY (0.46) | ACLYSGK1 | |
| SCHEMBL20354729 | 0.79 | ACLY (0.38) | ACLYSGK1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |