Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 9/20 | 0.43 |
| ▸ | ATIC | P31939 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354880 | 1.00 | ACLY (0.43) | ACLYATICSLC22A12NR3C1PGR | |
| SCHEMBL29560137 | 0.91 | ACLY (0.46) | ACLYATICSLC22A12NR3C1PGR | |
| SCHEMBL21545968 | 0.91 | ACLY (0.46) | ACLYATICSLC22A12NR3C1PGR | |
| SCHEMBL20339145 | 0.87 | SLC22A12 (0.45) | ACLYATICSLC22A12NR3C1PGR | |
| SCHEMBL29560169 | 0.87 | CCR2 (0.44) | ACLYATICSLC22A12NR3C1PGR | |
| SCHEMBL21545895 | 0.87 | CCR2 (0.44) | ACLYATICSLC22A12NR3C1PGR | |
| SCHEMBL20339152 | 0.85 | CCR2 (0.45) | ACLYTDO2SGK1 | |
| SCHEMBL34471802 | 0.85 | ACLY (0.43) | ACLYATICSLC22A12SGK1 | |
| SCHEMBL20339128 | 0.85 | ACLY (0.43) | ACLYATICSLC22A12SGK1 | |
| SCHEMBL20339035 | 0.83 | ATIC (0.42) | ACLYATICSLC22A12NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |