Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.79 |
| ▸ | GSR | P00390 | 1/20 | 0.64 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | JUN | P05412 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TFEB | P19484 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17973990 | 0.88 | HSD11B1 (1.00) | HSD11B1GSRLY96BCHENFKB1 | |
| SCHEMBL30317482 | 0.88 | HSD11B1 (1.00) | HSD11B1GSRLY96BCHENFKB1 | |
| SCHEMBL10448403 | 0.79 | NFKB1 (0.78) | HSD11B1GSRBCHENFKB1NFE2L2 | |
| SCHEMBL10448404 | 0.79 | NFKB1 (0.78) | HSD11B1GSRBCHENFKB1NFE2L2 | |
| SCHEMBL1049717 | 0.79 | HSD11B1 (0.74) | HSD11B1LY96BCHENFKB1KMT2A | |
| SCHEMBL1049718 | 0.79 | HSD11B1 (0.74) | HSD11B1LY96BCHENFKB1KMT2A | |
| SCHEMBL28827718 | 0.78 | GSR (0.64) | HSD11B1GSRNFKB1NFE2L2JUN | |
| SCHEMBL29428459 | 0.78 | GSR (1.00) | GSRNFKB1NFE2L2JUNKMT2A | |
| SCHEMBL9780865 | 0.77 | HSD11B1 (0.71) | HSD11B1GSRLY96BCHENFKB1 | |
| SCHEMBL1479962 | 0.77 | HSD11B1 (0.71) | HSD11B1LY96BCHENFKB1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850329-A | Cycloterpyriaryl phosphines, their preparation and use | 东莞市均成高新材料有限公司 | 2023-03-28 | — | — | CN | disclosed |