SCHEMBL28993773

SCHEMBL28993773

COc1cc(F)c(C2CNC(=O)[C@@H]2N)c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 20/20 0.55
FPR1 P21462 15/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28993770 1.00 FPR2 (0.55) FPR2FPR1
SCHEMBL29434330 1.00 FPR2 (0.55) FPR2FPR1
SCHEMBL22016004 1.00 FPR2 (0.55) FPR2FPR1
SCHEMBL28332794 1.00 FPR2 (0.55) FPR2FPR1
SCHEMBL18106453 1.00 FPR2 (0.55) FPR2FPR1
SCHEMBL18590525 0.83 FPR2 (0.40) FPR2FPR1
SCHEMBL20581283 0.82 FPR2 (0.55) FPR2FPR1
SCHEMBL22015872 0.82 FPR2 (0.61) FPR2FPR1
SCHEMBL20041873 0.82 FPR2 (0.44) FPR2FPR1
SCHEMBL18106704 0.80 FPR2 (0.56) FPR2FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166134-B Pyrrolidone derivatives as formyl peptide 2 receptor agonists 百时美施贵宝公司 2024-06-14 CN disclosed
CN-116034104-A Oxo-pyrrolidine FPR2 agonists 百时美施贵宝公司 2023-04-28 CN disclosed