Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 20/20 | 0.61 |
| ▸ | FPR1 | P21462 | 17/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21995818 | 0.85 | FPR2 (0.73) | FPR2FPR1CYP3A4 | |
| SCHEMBL20041944 | 0.84 | FPR2 (0.59) | FPR2FPR1CYP3A4 | |
| SCHEMBL18264179 | 0.83 | FPR2 (0.72) | FPR2FPR1CYP3A4 | |
| SCHEMBL18264180 | 0.83 | FPR2 (0.72) | FPR2FPR1CYP3A4 | |
| SCHEMBL29434330 | 0.82 | FPR2 (0.55) | FPR2FPR1 | |
| SCHEMBL18106453 | 0.82 | FPR2 (0.55) | FPR2FPR1 | |
| SCHEMBL22016004 | 0.82 | FPR2 (0.55) | FPR2FPR1 | |
| SCHEMBL28993770 | 0.82 | FPR2 (0.55) | FPR2FPR1 | |
| SCHEMBL28993773 | 0.82 | FPR2 (0.55) | FPR2FPR1 | |
| SCHEMBL28332794 | 0.82 | FPR2 (0.55) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395200-A1 | SYNTHETIC PROCESSES FOR THE PRODUCTION OF 1-((3S,4R)-4-(2,6-DIFLUORO-4-METHOXYPHENYL)-2-OXOPYRROLIDIN-3-YL)-3-PHENYLUREA | BRISTOL MYERS SQUIBB CO (US) | 2021-12-23 | — | — | US | disclosed |
| WO-2020102643-A1 | SYNTHETIC PROCESSES FOR THE PRODUCTION OF 1-((3S,4R)-4-(2,6-DIFLUORO-4-METHOXYPHENYL)-2-OXOPYRROLIDIN-3-YL)-3-PHENYLUREA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395200-A1 | SYNTHETIC PROCESSES FOR THE PRODUCTION OF 1-((3S,4R)-4-(2,6-DIFLUORO-4-METHOXYPHENYL)-2-OXOPYRROLIDIN-3-YL)-3-PHENYLUREA | UMPS, ODC1, DDC | FPR2 4139/4885FPR1 4407/4885CYP3A4 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.