Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 8/20 | 0.38 |
| ▸ | TLR4 | O00206 | 4/20 | 0.36 |
| ▸ | TLR2 | O60603 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25607559 | 0.83 | ALDH1A1 (0.39) | FBP1TLR4TLR2HSP90AA1KDM4E | |
| SCHEMBL27347920 | 0.71 | TRPM5 (0.46) | RXRANR4A2RXRBRXRGFFAR1 | |
| SCHEMBL30805880 | 0.70 | RXRA (0.41) | RXRANR4A2RXRBRXRGFFAR1 | |
| SCHEMBL14871662 | 0.70 | NR4A2 (0.41) | RXRANR4A2RXRBRXRGFFAR1 | |
| SCHEMBL27348074 | 0.70 | RXRA (0.41) | RXRANR4A2RXRBRXRGFFAR1 | |
| SCHEMBL30805849 | 0.70 | RXRA (0.41) | RXRANR4A2RXRBRXRGFFAR1 | |
| SCHEMBL1667201 | 0.70 | NR4A2 (0.41) | RXRANR4A2RXRBRXRGFFAR1 | |
| SCHEMBL18989919 | 0.70 | FFAR1 (0.47) | RXRANR4A2RXRBRXRGFFAR1 | |
| SCHEMBL2517572 | 0.70 | NR4A2 (0.41) | RXRANR4A2RXRBRXRGFFAR1 | |
| SCHEMBL27347349 | 0.70 | RXRA (0.41) | RXRANR4A2RXRBRXRGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867553-A | Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists | 巴格沃克斯研究有限公司 | 2023-03-28 | — | — | CN | disclosed |