SCHEMBL28994580

SCHEMBL28994580

CC(C)(C)c1ccc(-c2c(C(=O)Oc3ccccc3)cc(C(C)(C)C)c(O)c2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.43
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPSR1 Q6W5P4 2/20 0.42
POLB P06746 2/20 0.39
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
NSD2 O96028 1/20 0.36
ALOX5 P09917 1/20 0.36
PTGS2 P35354 1/20 0.36
CYP3A4 P08684 2/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
TBXA2R P21731 1/20 0.36
SLC6A2 P23975 1/20 0.36
PDE4A P27815 1/20 0.36
ADRA1A P35348 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30366235 1.00 MAPT (0.43) MAPTTDP1L3MBTL1NPSR1POLB
SCHEMBL93460 0.83 GLRA3 (0.41) MAPTTDP1POLBHSD17B10ALOX5
SCHEMBL11205006 0.80 APEX1 (0.46) MAPTTDP1L3MBTL1NPSR1POLB
SCHEMBL31230453 0.80 MAPT (0.46) MAPTTDP1L3MBTL1NPSR1ALOX5
SCHEMBL30931410 0.78 APEX1 (0.38) MAPTTDP1L3MBTL1NPSR1POLB
SCHEMBL11655997 0.78 TNFRSF1A (0.37) MAPTTDP1L3MBTL1POLBHSD17B10
SCHEMBL11115627 0.77 VCAM1 (0.33) LMNAMAPK1
SCHEMBL4201442 0.76 AKR1C2 (0.43) MAPTTDP1POLBHSD17B10HPGD
SCHEMBL9444896 0.76 TDP1 (0.41) MAPTTDP1L3MBTL1POLBHSD17B10
Benzotriazole SCHEMBL4989143 0.74 ALOX5 (0.33) MAPTTDP1ALOX5PTGS2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116075368-B Resin composition, cured product, method for producing same, and laminate 三菱化学株式会社 2024-06-11 CN disclosed
CN-116075368-A Resin composition, cured product, method for producing same, and laminate 三菱化学株式会社 2023-05-05 CN disclosed