Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27982197 | 0.92 | ANPEP (0.46) | ANPEPALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL28134518 | 0.85 | SIGMAR1 (0.47) | ANPEPALDH1A1MEN1MAPTKMT2A | |
| Acetic Acid SCHEMBL27901200 | 0.84 | MAOA (0.47) | ALDH1A1MEN1MAPTKMT2ASIGMAR1 | |
| Acetic Acid SCHEMBL27962834 | 0.83 | MAOA (0.46) | ALDH1A1MEN1MAPTKMT2ASIGMAR1 | |
| Acetic Acid SCHEMBL27962848 | 0.83 | MAOA (0.46) | ALDH1A1MEN1MAPTKMT2ASIGMAR1 | |
| Acetic Acid SCHEMBL29156192 | 0.82 | P2RY6 (0.36) | ANPEPALDH1A1MEN1KMT2ACYP1A2 | |
| Acetic Acid SCHEMBL28375367 | 0.82 | KMT2A (0.49) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| Acetic Acid SCHEMBL29156189 | 0.80 | TSHR (0.38) | ANPEPALDH1A1MEN1KMT2ACYP1A2 | |
| Acetic Acid SCHEMBL8076699 | 0.78 | OPRD1 (0.36) | MEN1KMT2ASIGMAR1OPRK1 | |
| Acetic Acid SCHEMBL8540399 | 0.75 | MEN1 (0.57) | ALDH1A1MEN1MAPTKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041529-A | anti-CD 3 antibodies and methods of use | 基因泰克公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-109608545-A | The anti-HER4 antibody of same type specificity | 健泰科生物技术公司 | 2019-04-12 | — | — | CN | disclosed |