Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MPO | P05164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951373 | 0.84 | KDM4E (0.46) | KDM4ELMNAPOLBCASP6NQO2 | |
| SCHEMBL11592944 | 0.81 | KDM4E (0.43) | KDM4ELMNAPOLBCASP6NQO2 | |
| SCHEMBL9861710 | 0.81 | LMNA (0.43) | KDM4ELMNAPOLBCASP6NQO2 | |
| SCHEMBL12501247 | 0.79 | LMNA (0.54) | KDM4ELMNANQO2SMN1; SMN2ALDH1A1 | |
| SCHEMBL12501269 | 0.78 | MPO (0.58) | KDM4EPOLBALDH1A1HSD17B10MPO | |
| SCHEMBL1857081 | 0.76 | ACHE (0.49) | KDM4ELMNAPOLBCASP6NQO2 | |
| SCHEMBL27931468 | 0.76 | KDM4E (0.46) | KDM4ELMNAPOLBCASP6NQO2 | |
| SCHEMBL12501194 | 0.76 | MPO (0.57) | KDM4EMPOACHE | |
| SCHEMBL12575811 | 0.76 | MPO (0.57) | KDM4ESMN1; SMN2ALDH1A1MPOCYP1A2 | |
| SCHEMBL31268127 | 0.76 | MPO (0.57) | KDM4ESMN1; SMN2ALDH1A1MPOCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041341-A | Quinazoline PAR4 antagonist and medical application thereof | 中国药科大学 | 2023-05-02 | — | — | CN | disclosed |