SCHEMBL2899548

SCHEMBL2899548

CC(C)(C)OC(=O)N[C@@H](CCC(N)=O)C(=O)OCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.54
CTSS P25774 4/20 0.51
PPARG P37231 2/20 0.51
SYK P43405 1/20 0.51
CTSK P43235 5/20 0.50
ACE P12821 1/20 0.50
CTSL P07711 1/20 0.49
CTSB P07858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
REN P00797 1/20 0.48
KLK7 P49862 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883348 1.00 PPARA (0.54) PPARACTSSPPARGSYKCTSK
SCHEMBL11291089 0.91 REN (0.54) PPARACTSSSYKCTSKSMN1; SMN2
SCHEMBL7290254 0.91 CTSK (0.54) PPARACTSSSYKCTSKCTSL
SCHEMBL957159 0.90 PPARA (0.56) PPARACTSSPPARGSYKCTSK
SCHEMBL2707177 0.90 PPARA (0.56) PPARACTSSPPARGSYKCTSK
SCHEMBL203720 0.90 PPARA (0.56) PPARACTSSPPARGSYKCTSK
SCHEMBL10054776 0.90 PPARA (0.56) PPARACTSSPPARGSYKCTSK
SCHEMBL27578688 0.90 PPARA (0.56) PPARACTSSPPARGSYKCTSK
SCHEMBL1517760 0.89 PPARA (0.55) PPARACTSSPPARGSYKCTSK
SCHEMBL3817109 0.89 PPARA (0.55) PPARACTSSPPARGSYKCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0815833-B1 Malodour preventing agents GIVAUDAN SA (CH) 2003-04-09 EP claimed
US-5925339-A ODORLESS DEODORANTS AND ANTIPERSPIRANTS GIVAUDAN ROURE SA (CH) 1999-07-20 US claimed
EP-0815833-A2 Malodour preventing agents GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1998-01-07 EP claimed
EP-2813512-B1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI PHARMACEUTICAL CO LTD (JP) 2021-03-31 EP disclosed
WO-2020198435-A1 SMALL MOLECULE DEGRADERS OF STAT3 THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2020-10-01 WO disclosed
WO-2013100132-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD 中外製薬株式会社 (JP) 2013-07-04 WO disclosed
US-7807678-B2 Peptidomimetics of biologically active metallopeptides PALATIN TECHNOLOGIES, INC. (US) 2010-10-05 US disclosed
US-20090253713-A1 Small Molecule Compositions for Sexual Dysfunction PALATIN TECHNOLOGIES, INC. (US) 2009-10-08 US disclosed
US-7550602-B1 Small molecule compositions for sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2009-06-23 US disclosed
US-7326707-B2 Bicyclic melanocortin-specific compounds PALATIN TECHNOLOGIES INCORPORATED (US) 2008-02-05 US disclosed
EP-1425029-A4 PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES PALATIN TECHNOLOGIES INC (US) 2006-06-07 EP disclosed
WO-2003013571-A1 PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2003-02-20 WO disclosed
US-6362165-B1 Hydroxyphenyl derivatives with HIV integrase inhibitory properties PHARMACOR INC. (CA) 2002-03-26 US disclosed
EP-1165492-A1 HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES Pharmacor Inc. (CA) 2002-01-02 EP disclosed
US-6150542-A COSMETICS; IN DEODORIZERS, ANTIPERSPIRANTS GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2000-11-21 US disclosed
WO-2000059867-A1 HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES PHARMACOR INC. (CA) 2000-10-12 WO disclosed
EP-0691422-B1 Process for the preparation of substituted diaminodicarboxylic acid derivatives NYCOMED AUSTRIA GMBH (AT) 1999-11-03 EP disclosed
US-5925339-A ODORLESS DEODORANTS AND ANTIPERSPIRANTS GIVAUDAN ROURE SA (CH) 1999-07-20 US disclosed
EP-0815833-A2 Malodour preventing agents GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1998-01-07 EP disclosed
EP-0691422-A1 Process for the preparation of substituted diaminodicarboxylic acid derivatives Hafslund Nycomed Pharma AG (AT) 1996-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253713-A1 Small Molecule Compositions for Sexual Dysfunction PDE3B, PDE3A, PDE5A PPARA 4448/4885CTSS 2907/4885PPARG 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.