Sugi Predict

Sugi Predict / Compounds / SCHEMBL203720

SCHEMBL203720

SCHEMBL203720

CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 3/20 0.56
▸ PPARG P37231 2/20 0.53
▸ SYK P43405 1/20 0.53
▸ CTSS P25774 4/20 0.53
▸ CTSK P43235 3/20 0.52
▸ ACE P12821 1/20 0.52
▸ CTSL P07711 1/20 0.51
▸ CTSB P07858 1/20 0.51
▸ ITGB3 P05106 1/20 0.51
▸ ITGA2B P08514 1/20 0.51
▸ FOLH1 Q04609 2/20 0.50
▸ KLK7 P49862 3/20 0.49
▸ MAPT P10636 1/20 0.49
▸ KLK5 Q9Y337 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL957159 1.00 PPARA (0.56) PPARAPPARGSYKCTSSCTSK
SCHEMBL2707177 1.00 PPARA (0.56) PPARAPPARGSYKCTSSCTSK
SCHEMBL27578688 0.93 PPARA (0.56) PPARAPPARGSYKCTSSCTSK
SCHEMBL10054776 0.93 PPARA (0.56) PPARAPPARGSYKCTSSCTSK
Glutamic Acid SCHEMBL4669203 0.92 PPARA (0.52) PPARAPPARGSYKCTSSCTSK
SCHEMBL1517760 0.91 PPARA (0.55) PPARAPPARGSYKCTSSCTSK
SCHEMBL3817109 0.91 PPARA (0.55) PPARAPPARGSYKCTSSCTSK
SCHEMBL14674671 0.91 CTSS (0.54) PPARAPPARGSYKCTSSCTSK
SCHEMBL15083152 0.90 PPARA (0.54) PPARAPPARGSYKCTSSCTSK
SCHEMBL10883348 0.90 PPARA (0.54) PPARAPPARGSYKCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721522-A A kind of high-quality N- tertbutyloxycarbonyl-L-Glutimic acid benzyl ester industrialized preparing process 常州吉恩药业有限公司 2019-05-07 — — CN claimed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 — — US disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 — — US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 — — EP disclosed
US-20250059213-A1 LONP1 INHIBITORS, USES AND METHODS PRETZEL THERAPEUTICS, INC. (US) 2025-02-20 — — US disclosed
US-20250059214-A1 AMIDE-CONTAINING LONP1 INHIBITOR COMPOUNDS, USES AND METHODS PRETZEL THERAPEUTICS, INC. (US) 2025-02-20 — — US disclosed
US-20240239842-A1 BINDING MOLECULE EXHIBITING SELECTIVE BINDING FOR RAS(G12D) MUTANT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-07-18 — — US disclosed
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-23 — — US disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 — — US disclosed
CN-117460743-A Small molecule VE-PTP inhibitors 曼宁研究公司 2024-01-26 — — CN disclosed
EP-2043658-A2 ANTIVIRAL PHOSPHINATE COMPOUNDS Gilead Sciences, Inc. (US) 2009-04-08 — — EP disclosed
WO-2008005565-A9 ANTIVIRAL PHOSPHINATE COMPOUNDS GILEAD SCIENCES INC (US) 2009-01-29 — — WO disclosed
US-20080275139-A1 Cyclodextrin-Containing Polymers and Uses Thereof CAPSUTECH LTD. (IL) 2008-11-06 — — US disclosed
EP-1976546-A2 CYCLODEXTRIN-CONTAINING POLYMERS AND USES THEREOF Capsutech Ltd. (IL) 2008-10-08 — — EP disclosed
US-20080057031-A1 Antiviral phosphinate compounds GILEAD SCIENCES, INC. (US) 2008-03-06 — — US disclosed
WO-2008005565-A2 ANTIVIRAL PHOSPHINATE COMPOUNDS GILEAD SCIENCES, INC. (US) 2008-01-10 — — WO disclosed
WO-2007072481-A2 CYCLODEXTRIN-CONTAINING POLYMERS AND USES THEREOF CAPSUTECH LTD. (IL) 2007-06-28 — — WO disclosed
US-4806557-A Dihydropyridines and use thereof in treating hypertension and ischaemia PFIZER INC. (US) 1989-02-21 — — US disclosed
EP-0136879-A2 Fatty acid derivatives and processes of producing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1985-04-10 — — EP disclosed
EP-0074761-A1 Peptide-type substrates useful in the quantitative determination of endotoxin WHITTAKER CORPORATION (US) 1983-03-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R PPARA 3215/4885PPARG 3973/4885SYK 1580/4885
US-20080057031-A1 Antiviral phosphinate compounds PHOSPHO1, MAVS, ITPA PPARA 1427/4885PPARG 3171/4885SYK 4689/4885
US-20240239842-A1 BINDING MOLECULE EXHIBITING SELECTIVE BINDING FOR RAS(G12D) MUTANT KRAS, G3BP1, G3BP2 PPARA 2535/4885PPARG 1461/4885SYK 4744/4885
US-20080275139-A1 Cyclodextrin-Containing Polymers and Uses Thereof IAPP, RNGTT, DDOST PPARA 2035/4885PPARG 3165/4885SYK 177/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 PPARA 2794/4885PPARG 3131/4885SYK 3527/4885
US-20250059213-A1 LONP1 INHIBITORS, USES AND METHODS LONP1, ACAT1, ACAA2 PPARA 2373/4885PPARG 2208/4885SYK 4456/4885
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R PPARA 3215/4885PPARG 3973/4885SYK 1580/4885
US-20250059214-A1 AMIDE-CONTAINING LONP1 INHIBITOR COMPOUNDS, USES AND METHODS LONP1, ACAT1, ACAA2 PPARA 1372/4885PPARG 1091/4885SYK 4628/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R PPARA 3215/4885PPARG 3973/4885SYK 1580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.