SCHEMBL28995656

SCHEMBL28995656

C#Cc1cnc(C)n1CC

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19497078 0.80 KDM4E (0.37) LMNASMN1; SMN2ALDH1A1THRBTSHR
SCHEMBL11908596 0.72
SCHEMBL14756121 0.72
SCHEMBL10235421 0.68 MAPK1 (0.33) LMNASMN1; SMN2ALDH1A1THRBTSHR
SCHEMBL13843803 0.68
SCHEMBL10183093 0.65 KDM4E (0.33) LMNASMN1; SMN2ALDH1A1THRBTSHR
SCHEMBL13467083 0.64 PTGER4 (0.36) LMNASMN1; SMN2ALDH1A1THRBTSHR
SCHEMBL19497079 0.63 ALDH1A1 (0.33) LMNASMN1; SMN2ALDH1A1THRBTSHR
SCHEMBL10281382 0.63 TLR7 (0.37) LMNASMN1; SMN2ALDH1A1TSHRMAPK1
SCHEMBL19497168 0.63 KDM4E (0.37) LMNASMN1; SMN2ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116057045-A Fibroblast growth factor receptor kinase inhibitors 金耐特生物制药公司 2023-05-02 CN disclosed