Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995960 | 0.74 | SMN1; SMN2 (0.44) | POLBRAB9ANPC1 | |
| SCHEMBL3512019 | 0.71 | HSD17B10 (0.47) | NPC1 | |
| SCHEMBL3512016 | 0.71 | HSD17B10 (0.47) | NPC1 | |
| SCHEMBL792043 | 0.71 | HSD17B10 (0.47) | NPC1 | |
| SCHEMBL792002 | 0.70 | HDAC8 (0.44) | PLATADORA2AROCK2ROCK1CNR2 | |
| SCHEMBL15317694 | 0.69 | POLB (0.54) | ADORA2AHDAC8HDAC6HDAC1POLB | |
| SCHEMBL26704171 | 0.69 | DPP4 (0.40) | PLATROCK2ROCK1CNR2HDAC8 | |
| SCHEMBL24348072 | 0.68 | RAB9A (0.41) | PLATROCK2ROCK1CNR2HDAC8 | |
| SCHEMBL25218793 | 0.68 | POLB (0.41) | PLATADORA2AROCK2ROCK1CNR2 | |
| SCHEMBL10223232 | 0.68 | RIPK1 (0.44) | ADORA2AROCK2ROCK1CNR2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |