Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5649629 | 0.76 | ALDH1A1 (0.45) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL29207663 | 0.75 | KDM4E (0.44) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL28995685 | 0.74 | PLAT (0.40) | RAB9ANPC1POLB | |
| SCHEMBL5650551 | 0.70 | HPGD (0.47) | SMN1; SMN2HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL31274248 | 0.70 | ALDH1A1 (0.36) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL5650420 | 0.69 | HPGD (0.48) | SMN1; SMN2HTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL5649651 | 0.69 | CYP2C9 (0.46) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL5647954 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL27577343 | 0.68 | ALDH1A1 (0.37) | SMN1; SMN2HTTMAPTALDH1A1POLB | |
| SCHEMBL5650297 | 0.68 | NPC1 (0.45) | SMN1; SMN2HTTMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |