Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995655 | 0.77 | MAPT (0.44) | MAPTGAAGLAHCAR3MAPK1 | |
| SCHEMBL24266297 | 0.75 | MAPT (0.42) | MAPTGAAGLAHCAR3MAPK1 | |
| SCHEMBL30263678 | 0.75 | HCAR3 (0.38) | MAPTGAAHCAR3MAPK1LMNA | |
| SCHEMBL28995708 | 0.75 | MAPT (0.51) | MAPTGAAGLAHCAR3MAPK1 | |
| SCHEMBL17896593 | 0.73 | MAPT (0.56) | MAPTGAAGLAHCAR3MAPK1 | |
| SCHEMBL29525723 | 0.73 | MAPT (0.56) | MAPTGAAGLAHCAR3MAPK1 | |
| SCHEMBL24463187 | 0.73 | ROCK2 (0.41) | MAPTGAAGLAROCK2 | |
| SCHEMBL28737547 | 0.72 | MAPT (0.55) | MAPTGAAGLAHCAR3MAPK1 | |
| SCHEMBL34472545 | 0.72 | HCAR3 (0.40) | MAPTGAAGLAHCAR3MAPK1 | |
| SCHEMBL9847865 | 0.71 | MAPT (0.41) | MAPTGAAGLAHCAR3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |