Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657225 | 0.75 | MAPT (0.51) | MAPTALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL9847939 | 0.74 | KMT2A (0.34) | MAPTALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL9847875 | 0.74 | ALDH1A1 (0.44) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL8398485 | 0.72 | HCAR3 (0.47) | MAPTALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL2217900 | 0.72 | MAPT (0.51) | MAPTALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL28995655 | 0.72 | MAPT (0.44) | MAPTALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL28995768 | 0.71 | MAPT (0.41) | MAPTALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL24266297 | 0.70 | MAPT (0.42) | MAPTALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL34472545 | 0.70 | HCAR3 (0.40) | MAPTALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL21713321 | 0.70 | MAPT (0.47) | MAPTALDH1A1LMNASMN1; SMN2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | claimed |