Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 5/20 | 0.58 |
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | METAP2 | P50579 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCR9 | P51686 | 2/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | UQCRB | P14927 | 1/20 | 0.46 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191250 | 0.87 | HSD17B2 (0.49) | HSD17B2KDM1AMETAP2LMNAMAPT | |
| SCHEMBL28995990 | 0.84 | LMNA (0.67) | METAP2LMNAHTTTP53MAPT | |
| SCHEMBL29191237 | 0.82 | METAP2 (0.50) | METAP2LMNAHTTTP53MAPT | |
| SCHEMBL28995980 | 0.82 | KCNA5 (0.57) | METAP2LMNAHTTTP53MAPT | |
| SCHEMBL28996025 | 0.82 | ALDH1A1 (0.51) | KDM1AMETAP2LMNAHTTTP53 | |
| SCHEMBL28995965 | 0.82 | LMNA (0.51) | METAP2LMNAHTTTP53MAPT | |
| SCHEMBL28996151 | 0.82 | METAP2 (0.62) | METAP2LMNAHTTTP53MAPT | |
| SCHEMBL28995936 | 0.81 | MCL1 (0.60) | HSD17B2KDM1AMETAP2LMNAHTT | |
| SCHEMBL13852837 | 0.80 | HSD17B2 (0.68) | HSD17B2LMNAHTTMAPTCYP2C9 | |
| SCHEMBL23200380 | 0.80 | KDM1A (0.79) | KDM1AMETAP2LMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082269-B | 1,3, 4-Oxazoline compound containing trifluoromethyl quaternary carbon center and preparation method thereof | 盐城工学院 | 2024-06-21 | — | — | CN | disclosed |
| CN-116082269-A | 1,3, 4-oxazoline compound containing trifluoromethyl quaternary carbon center and preparation method thereof | 盐城工学院 | 2023-05-09 | — | — | CN | disclosed |