Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30252639 | 1.00 | KDM4E (0.50) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31015127 | 0.84 | KDM4E (0.53) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31015059 | 0.80 | KDM4E (0.54) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12813743 | 0.78 | KDM4E (0.53) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7385367 | 0.78 | KDM4E (0.57) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30643023 | 0.74 | KDM4E (0.60) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12615343 | 0.74 | KDM4E (0.60) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31015416 | 0.74 | ALDH1A1 (0.54) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7384813 | 0.73 | KDM4E (0.48) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21258879 | 0.72 | KDM4E (0.53) | KDM4EMEN1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651358-B | 4-aminopyridine derivative, pharmaceutical composition, preparation method and application thereof | 上海迪诺医药科技有限公司 | 2023-04-07 | — | — | CN | disclosed |