Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25436123 | 0.89 | GRM5 (0.39) | GRM5KMT2ASMN1; SMN2HSD17B10FABP4 | |
| SCHEMBL28996388 | 0.86 | GRM5 (0.42) | GRM5KMT2ASMN1; SMN2HSD17B10FABP4 | |
| SCHEMBL26650942 | 0.84 | GRM5 (0.37) | GRM5KMT2ASMN1; SMN2HSD17B10POLB | |
| SCHEMBL23658928 | 0.83 | HTR6 (0.42) | KMT2ASMN1; SMN2FABP4FABP5HTR6 | |
| SCHEMBL28996389 | 0.81 | PTGS2 (0.40) | KMT2AFABP4FABP5POLBHTR6 | |
| SCHEMBL30287358 | 0.81 | PTGS2 (0.40) | KMT2AFABP4FABP5POLBHTR6 | |
| SCHEMBL25317303 | 0.79 | SMN1; SMN2 (0.41) | GRM5KMT2ASMN1; SMN2HSD17B10POLB | |
| SCHEMBL30287349 | 0.77 | MEN1 (0.36) | GRM5KMT2AFABP4FABP5HTR6 | |
| SCHEMBL28997127 | 0.77 | MEN1 (0.36) | GRM5KMT2AFABP4FABP5HTR6 | |
| SCHEMBL25313711 | 0.74 | NFE2L2 (0.35) | KMT2ASMN1; SMN2HSD17B10POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884968-B | Novel acid secretion inhibitor and use thereof | 日东制药株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-115884968-A | Novel acid secretion inhibitor and use thereof | 日东制药株式会社 | 2023-03-31 | — | — | CN | disclosed |