Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091283 | 0.92 | PAOX (0.60) | L3MBTL1PAOXSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL31008699 | 0.91 | L3MBTL1 (0.68) | L3MBTL1PAOXSMN1; SMN2SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7427001 | 0.90 | PAOX (0.58) | L3MBTL1PAOXSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL3321939 | 0.88 | L3MBTL1 (0.68) | L3MBTL1PAOXSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL30479937 | 0.85 | PAOX (0.72) | L3MBTL1PAOXTSHRSIGMAR1ALDH1A1 | |
| SCHEMBL3926676 | 0.84 | L3MBTL1 (0.75) | L3MBTL1SMN1; SMN2CYP1A2MAPK1TSHR | |
| SCHEMBL2852219 | 0.82 | L3MBTL1 (0.65) | L3MBTL1PAOXSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL493879 | 0.82 | L3MBTL1 (0.79) | L3MBTL1SMN1; SMN2CYP1A2MAPK1TSHR | |
| Hydrochloric Acid SCHEMBL4710262 | 0.82 | L3MBTL1 (0.72) | L3MBTL1SMN1; SMN2CYP1A2MAPK1TSHR | |
| SCHEMBL13621202 | 0.81 | SIGMAR1 (0.54) | L3MBTL1PAOXTSHRSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182308-B1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARM SPA (IT) | 2024-09-04 | — | — | EP | disclosed |
| CN-116096719-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-09 | — | — | CN | disclosed |