Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.49 |
| ▸ | BCL2A1 | Q16548 | 6/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28996908 | 1.00 | FFAR1 (0.49) | FFAR1BCL2A1TEAD1PPARDPPARA | |
| SCHEMBL29369580 | 0.90 | FFAR1 (0.44) | FFAR1BCL2A1SLC6A2SLC6A4TLR7 | |
| SCHEMBL28997016 | 0.90 | FFAR1 (0.44) | FFAR1BCL2A1SLC6A2SLC6A4TLR7 | |
| SCHEMBL29366854 | 0.80 | TRPV1 (0.41) | TEAD1 | |
| SCHEMBL28996931 | 0.80 | TRPV1 (0.41) | TEAD1 | |
| SCHEMBL29369539 | 0.80 | RORC (0.35) | FFAR1BCL2A1 | |
| SCHEMBL28997587 | 0.80 | RORC (0.35) | FFAR1BCL2A1 | |
| SCHEMBL28996993 | 0.78 | TGM2 (0.53) | FFAR1TEAD1PPARDPPARA | |
| SCHEMBL28997537 | 0.76 | TGM2 (0.53) | FFAR1TEAD1SLC6A4 | |
| SCHEMBL28996914 | 0.76 | TGM2 (0.53) | FFAR1TEAD1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057042-B | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2024-10-18 | — | — | CN | claimed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | claimed |
| CN-116057042-B | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2024-10-18 | — | — | CN | disclosed |
| EP-4188907-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2023-06-07 | — | — | EP | disclosed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |
| WO-2022023460-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2022-02-03 | — | — | WO | disclosed |