Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 9/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 2/20 | 0.33 |
| ▸ | TGM1 | P22735 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997042 | 0.88 | MTNR1A (0.40) | MTNR1ATGM2CDK7CDK13EGFR | |
| SCHEMBL28997074 | 0.84 | MTNR1A (0.38) | MTNR1ATGM2CDK7CDK13EGFR | |
| SCHEMBL28997008 | 0.84 | MTNR1A (0.39) | MTNR1ATGM2EGFRKCNA5TDP2 | |
| SCHEMBL28996998 | 0.84 | MTNR1A (0.38) | MTNR1ATGM2CDK7CDK13EGFR | |
| SCHEMBL28997061 | 0.81 | TGM2 (0.44) | MTNR1ATGM2TDP2F13A1TGM1 | |
| SCHEMBL28997062 | 0.80 | TGM2 (0.39) | MTNR1ATGM2CDK7CDK13EGFR | |
| SCHEMBL28997071 | 0.79 | TGM2 (0.40) | MTNR1ATGM2EGFRKCNA5TDP2 | |
| SCHEMBL26332962 | 0.78 | TGM2 (0.38) | MTNR1ATGM2EGFRKCNA5F13A1 | |
| SCHEMBL29370014 | 0.77 | TGM2 (0.38) | MTNR1ATGM2EGFRKCNA5F13A1 | |
| SCHEMBL29367337 | 0.74 | TGM2 (0.44) | MTNR1ATGM2CDK7CDK13EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | claimed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |