Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406609 | 0.88 | ALDH1A1 (0.60) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL8628036 | 0.78 | KMT2A (0.70) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| Hydrochloric Acid SCHEMBL28888962 | 0.77 | KMT2A (0.68) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL249717 | 0.76 | CYP1A2 (0.55) | ALDH1A1KMT2AKDM4EPOLBHPGD | |
| SCHEMBL29792825 | 0.76 | CYP1A2 (0.55) | ALDH1A1KMT2AKDM4EPOLBHPGD | |
| SCHEMBL1408871 | 0.76 | ALDH1A1 (0.69) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL29863459 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL167452 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL5205165 | 0.76 | KDM4E (0.49) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL5746405 | 0.76 | CYP1A2 (0.55) | ALDH1A1KMT2ARAB9AGAARCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102495-A | 1,2,3, 4-tetrahydro-9-aminoacridine compound and application thereof | 浙江工业大学 | 2023-05-12 | — | — | CN | disclosed |