Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744660 | 0.86 | TRPV4 (0.41) | TRPV4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL809118 | 0.83 | TRPV4 (0.50) | TRPV4DHODHSTAT3 | |
| SCHEMBL4436602 | 0.82 | TRPV4 (0.41) | TRPV4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL3191466 | 0.82 | TRPV4 (0.46) | TRPV4KDM4EALDH1A1MAPTHSD17B10 | |
| Acetonitrile SCHEMBL23071362 | 0.81 | TRPV4 (0.44) | TRPV4DHODHGAAGFERSTAT3 | |
| SCHEMBL13082286 | 0.77 | TRPV4 (0.41) | TRPV4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL26377802 | 0.77 | RAPGEF4 (0.31) | — | |
| Cyclopropane SCHEMBL28838233 | 0.76 | TRPV4 (0.44) | TRPV4KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7649737 | 0.74 | TRPV4 (0.45) | TRPV4ALDH1A1 | |
| SCHEMBL5338291 | 0.74 | TRPV4 (0.45) | TRPV4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427801-A1 | FUNCTIONALIZED PERFLUOROPOLYETHER MATERIAL AS A HYDROPHOBIC COATING | Hewlett-Packard Development Company, L.P. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128969-A1 | FUNCTIONALIZED PERFLUOROPOLYETHER MATERIAL AS A HYDROPHOBIC COATING | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2010-11-11 | — | — | WO | disclosed |