Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744660 | 0.86 | TRPV4 (0.41) | TRPV4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL16122693 | 0.83 | KDM4E (0.43) | TRPV4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL3191466 | 0.82 | TRPV4 (0.46) | TRPV4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL289995 | 0.82 | TRPV4 (0.41) | TRPV4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL809217 | 0.78 | TRPV4 (0.52) | TRPV4STAT3 | |
| SCHEMBL29728453 | 0.78 | TRPV4 (0.52) | TRPV4STAT3 | |
| SCHEMBL16122308 | 0.77 | TRPV4 (0.46) | TRPV4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL313724 | 0.77 | RAPGEF4 (0.31) | — | |
| SCHEMBL7866631 | 0.74 | TRPV4 (0.45) | TRPV4ALDH1A1STAT3 | |
| SCHEMBL25786493 | 0.74 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125931-A1 | VINYL ENDS MEASURING METHOD | Eastman Chemical Company (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008097416-A1 | VINYL ENDS MEASURING METHOD | EASTMAN CHEMICAL COMPANY (US) | 2008-08-14 | — | — | WO | claimed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| EP-2125931-A1 | VINYL ENDS MEASURING METHOD | Eastman Chemical Company (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008097416-A1 | VINYL ENDS MEASURING METHOD | EASTMAN CHEMICAL COMPANY (US) | 2008-08-14 | — | — | WO | disclosed |