Isopropylamine

Isopropylamine

SCHEMBL28999841

CC(C)N.C[SiH](Cl)c1ccccc1

nearest known ligand 0.42

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.38
SLC6A2 P23975 2/20 0.38
TAAR1 Q96RJ0 2/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
CYP2A6 P11509 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
LMNA P02545 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP2D6 P10635 1/20 0.35
ALDH1A1 P00352 1/20 0.35
DPP4 P27487 2/20 0.35
F2 P00734 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448267 0.87
SCHEMBL28165355 0.82 TSHR (0.33) LMNA
Tert-Butylamine SCHEMBL28999847 0.81 TAAR1 (0.38) SLC6A2TAAR1
SCHEMBL24114402 0.73
SCHEMBL705419 0.70 TDP1 (0.33) MAOASLC6A2TAAR1SLC6A4SLC6A3
Chlorobenzene SCHEMBL27564205 0.69 TSHR (0.65) MAOASLC6A2TAAR1SLC6A4SLC6A3
Biphenyl SCHEMBL1556544 0.68 ALDH1A1 (0.60) MAOASLC6A2TAAR1SLC6A4SLC6A3
SCHEMBL4517726 0.68 TSHR (0.37) LMNAALDH1A1
SCHEMBL8992273 0.67 TDP1 (0.35) MAOASLC6A2TAAR1SLC6A4SLC6A3
Benzene SCHEMBL8083198 0.66 SLC6A2 (0.40) MAOASLC6A2TAAR1SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111148748-B Novel indene-based transition metal compound, transition metal catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using the same 沙特基础工业爱思开NEXLENE私人有限公司 2023-05-16 CN disclosed